Primary Identifier | MGI:5440844 | Allele Type | Targeted |
Gene | Pcdhg | Transmission | Germline |
Strain of Origin | 129S4/SvJae | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The genomic sequence encoding Pcdhgc3, Pcdhgc4 and Pcdhgc5 was replaced with a floxed construct containing a self-excising neo cassette. Cre-mediated recombination removed the neo cassette. By deleting three variable exons, this allele is a knock-out of three C-type isoforms (TCKO). |