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Allele : Gjb2<tm3.1(Gjb1)Kwi> gap junction protein, beta 2; targeted mutation 3.1, Klaus Willecke
Primary Identifier  MGI:5441202 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gjb2
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  Flp-mediated recombination of Gjb2tm3(Gjb1)Kwi removed the neo cassette. Further cre-mediated recombination is required to remove the floxed lacZ and allow expression of the inserted coding sequence. Western blot analysis confirmed reduced protein expression in the placenta but not skin.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Cx26<floxlacZ[Cx32]>,
  • Cx26<floxlacZ[Cx32]>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

5 Publication categories





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