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Allele : Syk<tm2.1(ZAP70)Fkfr> spleen tyrosine kinase; targeted mutation 2.1, Friedemann Kiefer
Primary Identifier  MGI:5442724 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Syk
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The coding sequence in exon 2 was replaced with a human cDNA for Zap70 and an FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette. Western blot analysis confirmed the absence of endogenous protein expression and expression of the human cDNA.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Syk<ki>,
  • Syk<ki>,
  • Syk<Zap-70>,
  • Syk<Zap-70 delta>,
  • Syk<Zap-70 delta>,
  • Syk<Zap-70>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories





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