Primary Identifier | MGI:5442732 | Allele Type | Spontaneous |
Gene | Tyr | Inheritance Mode | Recessive |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The mutation is a 14.3 kb deletion of the tyrosinase gene spanning from 940 bp 5' of exon 1 (including the minimal promoter region) to 3.75 kb 3' of exon 2. This mutation arose spontaneously in EUCOMM embryonic stem (ES) cell clone EPD0176_3_A10, which was produced from JM8.N4 embryonic stem (ES) cells. |