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Allele : Tph2<tm1.1Pasq> tryptophan hydroxylase 2; targeted mutation 1.1, Massimo Pasqualetti

Primary Identifier	MGI:5442737	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Tph2
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

One hundred and five nucleotides downstream of the first ATG codon were replaced by a cDNA for EGFP and an FRT flanked neomycin selection cassette. The neo selection cassette was subsequently removed by flp recombinase expression.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Migliarini S, et al. (2013) Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Mol Psychiatry 18(10):1106-18

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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