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Allele : Rspo3<tm1.1Jcob> R-spondin 3; targeted mutation 1.1, John Cobb

Primary Identifier	MGI:5443941	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Rspo3
Transmission	Germline	Strain of Origin	(129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Rspo3<F>,
Rspo3<F>

earliestPublication:
Neufeld S, et al. (2012) A conditional allele of Rspo3 reveals redundant function of R-spondins during mouse limb development. Genesis 50(10):741-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

14 Publication categories

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