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Allele : Gucy1b2<tm2Mom> guanylate cyclase 1, soluble, beta 2; targeted mutation 2, Peter Mombaerts

Primary Identifier  MGI:5444154 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gucy1b2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Approximately 4.3 kb of DNA encoding the catalytic domain, spanning from partway through exon 12 to partway through of exon 15, was deleted, a stop codon and AscI site was generated in the middle of exon 12, and an IRES-tauGFP-pA ACNF cassette was inserted into the AscI site thus creating a null allele with GFP reporter.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gucy1b2-KO,
  • Gucy1b2-D-IRES-tauGFP,
  • Gucy1b2-D-IRES-tauGFP,
  • Gucy1b2-KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories