Primary Identifier | MGI:5446381 | Allele Type | Targeted |
Attribute String | Null/knockout, Transactivator | Gene | Sox1 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The open reading frame was replaced with a tetracycline transactivator (tTA) and polyadenylation sequence. Cre-mediated recombination removed the floxed neo cassette inserted downstream of the tTA. Immunohistochemistry confirmed the absence of protein expression. |