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Allele : Tg(Krt18-EGFP,-TAg121)36Ysng transgene insertion 36, Yurong Song
Primary Identifier  MGI:5449063 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Krt18-EGFP,-TAg121)36Ysng
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Mice from this transgenic line carry a bacterial artificial chromosome (BAC) containing the mouse keratin 18 gene, into which a loxP-GFP-stop-loxP (LSL) T121 (the N-terminal domain of SV40 large T antigen) cassette was inserted. This line exibits epithelial-specific Cre-dependent expression of T121 to dominantly interfere with all 3 pocket proteins (pRB, p107, and p130), facilitating RB-TS inactivation in vivo with a single construct. One copy of the transgene was observed in mice from line 36.
  • mutations:
  • Insertion
  • synonyms:
  • TgK18GT121<tg>,
  • TgK18GT121 Line 36,
  • TgK18GT121 Line 36,
  • Tg(K18GT121)Tvd,
  • TgK18GT121-36,
  • TgK18GT121,
  • TgK18GT121-36,
  • TgK18GT121,
  • Tg(K18GT121)Tvd,
  • TgK18GT121<tg>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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7 Publication categories





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