| Primary Identifier | MGI:5450813 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase, Reporter | Gene | Cx3cr1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | A targeting vector was designed to replace exon 2 of the chemokine (C-X3-C) receptor 1 (Cx3cr1) gene with a cre/ERT2 (cre recombinase fused to an estrogen receptor ligand binding domain) coding sequence, followed by an internal ribosome entry site (IRES) and an enhanced yellow fluorescent protein (EYFP). A frt-flanked neomycin resistance cassette, in reverse orientation to the gene, was also inserted downstream of the EYFP sequence. Flp-mediated recombination excised the neomycin resistance sequence. |
