| Help | About | Contact Us

Allele : Rest<tm1.2Yasu> RE1-silencing transcription factor; targeted mutation 1.2, Yasuhiro Yamada

Primary Identifier	MGI:5450876	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Rest
Transmission	Germline	Strain of Origin	(C57BL/6 x 129S4/SvJae)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 4 was replaced with a construct containing the following elements: loxP site, exon 4, IRES, GFP, loxP, neo cassette, and loxP site. Cre mediated recombination removed the neo cassette, exon 4 and the GFP gene.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Yamada Y, et al. (2010) Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell 6(1):10-5

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76442276

MouseMine