| Primary Identifier | MGI:5447065 | Allele Type | Transgenic |
| Attribute String | Constitutively active, Inserted expressed sequence | Gene | Tg(Neurod2-Smo*A2)#Jols |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The ND2:SmoA2 transgene contains the entire mouse smoothened homolog (Drosophila) Smo gene, with the constitutively active point mutation SmoA2 (S537N), driven by the 1kb mouse neurogenic differentiation 2 (Neurod2) promoter. Four lines were generated (221, 222, 225 and 242). All lines exhibit a low level of transgene expression (4-, 1-, 3- and 2-fold, respectively for each line relative to wild-type levels). The pound symbol (#) is used when no line is specified and/or lines are pooled. |
