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Allele : Mir378a<tm1.1Eno> microRNA 378a; targeted mutation 1.1, Eric N Olson

Primary Identifier	MGI:5448834	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Mir378a
Transmission	Germline	Strain of Origin	129S/SvEv
Is Recombinase	false	Is Wild Type	false

molecularNote

The microRNA sequence was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. qRT-PCR confirmed the absence of transcript expression. Western blot analysis confirmed normal protein expression of the host gene.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Carrer M, et al. (2012) Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*. Proc Natl Acad Sci U S A 109(38):15330-5

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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