| Primary Identifier | MGI:5449356 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Vsx2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A self excising selection cassette (ACN) was inserted in intron 3 and the bases agg were changed to tgg in exon 4 via homologous recombination. The base changes result in an arginine to tryptophan substitution at position 227 (R227W). Cre mediated recombination in the male germ line removed the selection cassette. Protein expression is similar to wild-type protein but DNA binding is reduced. |
