| Primary Identifier | MGI:5450726 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Il10ra |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT flanked PGK neo resistance cassette was inserted in intron 2 and loxP sites were inserted flanking exon 3. Subsequent expression of flp recombinase removed the selection cassette leaving exon 3 flanked by loxP sites. Exon 3 contains much of the Il10 interacting domain. Genomic loss of exon 3 was observed in T cells expressing cre under the control of the Cd4 promoter by PCR analysis. |
