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Allele : Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa transgene insertion, Timothy J Sargeant

Primary Identifier  MGI:5451192 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence, Transactivator Gene  Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa
Strain of Origin  C57BL/6 x CBA Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The human SYN1 promoter drives expression of the tet-transactivator from the pTet-off advanced plasmid and tet responsive element (TRE-tight) drives expression of a full lenght mouse Hexb cDNA. Expression is seen only in the nervous tissue. In the cerebral cortex, the tet-transactivator transcript is strongly expressed in layer 6b neurons.
  • mutations:
  • Insertion
  • synonyms:
  • P8SYN (+),
  • SYN<Tg>,
  • SYN<Tg>,
  • P8SYN (+)
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories