Primary Identifier | MGI:5451192 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence, Transactivator | Gene | Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa |
Strain of Origin | C57BL/6 x CBA | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The human SYN1 promoter drives expression of the tet-transactivator from the pTet-off advanced plasmid and tet responsive element (TRE-tight) drives expression of a full lenght mouse Hexb cDNA. Expression is seen only in the nervous tissue. In the cerebral cortex, the tet-transactivator transcript is strongly expressed in layer 6b neurons. |