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Allele : Cerkl<tm1.1Geno> ceramide kinase-like; targeted mutation 1.1, Genoway
Primary Identifier  MGI:5461515 Allele Type  Targeted
Attribute String  Hypomorph Gene  Cerkl
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted usptream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. Semi-quantitative RT-PCR confirmed reduced transcript expression in the retina, kidney, liver, spleen and testis. This allele is hypomorphic.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories





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