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Allele : Atm<tm1Shzh> ataxia telangiectasia mutated; targeted mutation 1, Shan Zha

Primary Identifier  MGI:5463796 Allele Type  Targeted
Gene  Atm Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 3 was replaced with a floxed neo cassette and a modified exon 3 in which an A to C and T to A transversion results in the amino acid substitutions of aspartic acid for alanine at position 2870 (A2870D) and lysine for asparagine at position 2875 (N2875K). These mutations result in a kinase dead protein.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • ATM<KDN>,
  • ATM<KDN>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories