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Allele : Tg(APOE-FGF23*R176Q)#Ack transgene insertion, Andrew C Karaplis

Primary Identifier  MGI:5465569 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(APOE-FGF23*R176Q)#Ack
Strain of Origin  C57BL/6J x CBA Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of the human APOE promoter with exon 1 and part of exon 2 and the human FGF23 cDNA with the R176Q mutation tagged with a myc epitope followed by the APOE poly(A) and hepatic control region. The APOE promoter drives expression of FGF23 in the liver. Two lines were established however, the pound symbol (#) is used because the line is not specified and lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • FGF23-TG,
  • FGF23-TG
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories