Primary Identifier | MGI:5465569 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(APOE-FGF23*R176Q)#Ack |
Strain of Origin | C57BL/6J x CBA | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of the human APOE promoter with exon 1 and part of exon 2 and the human FGF23 cDNA with the R176Q mutation tagged with a myc epitope followed by the APOE poly(A) and hepatic control region. The APOE promoter drives expression of FGF23 in the liver. Two lines were established however, the pound symbol (#) is used because the line is not specified and lines are pooled. |