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Allele : Gt(ROSA)26Sor<tm1(Eif1a-tTA,tetO-mCherry/HTR4*D100A)Conk> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bruce Conklin
Primary Identifier  MGI:5468098 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence, Reporter, Transactivator Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129P2/OlaHsd
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  A combined EF1a-tTA and TetO-mCh/Rs1 transgene in a single construct (separated by a 2A ribosomal skip site) was inserted in the Gt(ROSA)26Sor locus. Rs1 is an engineered Gs-coupled G-protein coupled receptor in which an aspartic acid to alanine amino acid residue change at position 100 was made to generate serotonin-insensitive GPCR.
  • mutations:
  • Insertion
  • synonyms:
  • TetO-mCh-Rs1,
  • R26(EF1a-tTA/TetO-mCh-Rs1),
  • TetO-mCh-Rs1,
  • R26(EF1a-tTA/TetO-mCh-Rs1)
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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