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Allele : Tc(HSA7;HSA14)#Mtos transchromosomal, human 7 and human 14, Mitsuo Oshimura
Primary Identifier  MGI:5469115 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tc(HSA7;HSA14)#Mtos
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination and telomere seeding resulted in the transfer a portion of human chromosome 7 (from the AC004922 and AF006752; including the CYP3A cluster) onto the human artificial chromosome (HAC; SC20) generated from human chromosome 14. The HAC contains an GFP, loxP site and hygro cassette at AC004922 locus. A xenobiotic-responsive element results in liver-specific expression of the CYP3A-HAC induced by rifampicin treatment.
  • mutations:
  • Insertion
  • synonyms:
  • CYP3A-HAC,
  • CYP3A-HAC
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1 Feature

Genome

4 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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