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Allele : Cxcl12<tm1.1Link> C-X-C motif chemokine ligand 12; targeted mutation 1.1, Daniel C Link

Primary Identifier	MGI:5468835	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Cxcl12
Transmission	Germline	Strain of Origin	C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 2. A floxed neo cassette was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette and left exon 2 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Cxcl12<fl>,
Cxcl12<fl>

earliestPublication:
Greenbaum A, et al. (2013) CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature 495(7440):227-30

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

32 Publication categories

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