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Allele : Soat2<tm1.2Llr> sterol O-acyltransferase 2; targeted mutation 1.2, Lawrence L Rudel

Primary Identifier  MGI:5469867 Allele Type  Targeted
Attribute String  Null/knockout Gene  Soat2
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT and loxP flanked neo cassette was inserted upstream of exon 11. An additionally loxP site was inserted downstream of exon 13. Enzymatic assay confirmed less than 10% normal activity levels. Flp-mediated recombination removed the neo cassette and left exons 11 through 13 floxed. Cre mediated excision then removed exons 11 through 13.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories