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Allele : Cdkn2a<tm3.1Nesh> cyclin dependent kinase inhibitor 2A; targeted mutation 3.1, Norman E Sharpless
Primary Identifier  MGI:5471230 Allele Type  Targeted
Attribute String  Modified isoform(s), Reporter Gene  Cdkn2a
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Exon1alpha was replaced with a translation start site, firefly luciferase cDNA and FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette. Western blot analysis confirmed the lack of p16INK4a isoform expression. Expression of isoforms p19ARF and p15INK4b is not affected.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p16<LUC>,
  • p16<LUC>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

14 Publication categories





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