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Allele : Dlk1<tm1.2Jvs> delta like non-canonical Notch ligand 1; targeted mutation 1.2, Jennifer V Schmidt

Primary Identifier  MGI:5471922 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dlk1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Phenotypes observed are dependent on parental source of the allele.
molecularNote  Cre-mediated recombination removed a neo selection cassette and the last two exons (5 and 6). Northern blot analysis confirmed severely reduced level of transcript expression in E12.5 embryo and placenta when this allele is inherited paternally.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Dlk1<cons>,
  • Dlk1<cons>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories