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Allele : Dll1<tm1.1(cre/ERT2)Cle> delta like canonical Notch ligand 1; targeted mutation 1.1, Hans Clevers

Primary Identifier  MGI:5473277 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Dll1
Transmission  Germline Strain of Origin  Not Specified
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  Homologous recombination was employed to insert an EGFP-IRES-cre/ERT2 cassette, Frt-flanked neo selection cassette and polyA signal into the ATG codon of exon 1 of Dll1 in ES cells. The neo marker was deleted in vivo by flippase (Flp) expression. GFP expression can be detected by confocal analysis in some mesenchymal cells and blood vessels, and in intestinal epithelial cells at the bottom and higher up in crypts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dll1<GFP-Creert2>,
  • Dll1<GFP-Creert2>,
  • Dll1<GFP-ires-CreERT2>,
  • Dll1<GFP-ires-CreERT2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

7 Publication categories