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Allele : Col1a1<tm2(tetO-CTNNB1*)Hoch> collagen, type I, alpha 1; targeted mutation 2, Konrad Hochedlinger

Primary Identifier  MGI:5473958 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm2(tetO-Pou5f1)Jae (J:159351).
molecularNote  RMCE was used to insert a human beta-catenin sequence containing an S33Y codon substitution under the control of a tetO and a minimal promoter. Insertion was in the 3' non coding region.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories