| Primary Identifier | MGI:5476822 | Allele Type | Targeted |
| Gene | Pkd1 | Transmission | Germline |
| Strain of Origin | 129 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 29 was replaced with a modified exon in which arginine codon 3269 (AGA) was changed to cysteine (TGC) (c.9805.9807AGA>TGC, p.R3269C), which corresponds to the human autosomal dominant polycystic kidney disease (ADPKD)-associated p.R3277C mutation. Cre-mediated recombination removed a floxed puromycin cassette inserted downstream of exon 30. |
