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Allele : Gabrg2<tm2Spet> gamma-aminobutyric acid type A receptor, subunit gamma 2; targeted mutation 2, Steven Petrou

Primary Identifier  MGI:5474655 Allele Type  Targeted
Attribute String  Hypomorph Gene  Gabrg2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The coding region was replaced with a coding region containing substitution that results in an amino acid substution of a glutamine for an arginine at position 43 (R43Q), 4 additional silent mutations (not identified) and a floxed neo cassette. This allele is hypomorphic and was used to generate Gabrg2tm1Spet. QPCR confirms reduced transcript expression at P15 and P66.
  • mutations:
  • Insertion
  • synonyms:
  • gamma2<Q43neo>,
  • Gabrg2<Qneo>,
  • gamma2<Q43neo>,
  • Gabrg2<Qneo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories