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Allele : Gclc<tm1c(EUCOMM)Wtsi> glutamate-cysteine ligase, catalytic subunit; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5475270 Allele Type  Targeted
Attribute String  Conditional ready Gene  Gclc
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_gt0 cassette was inserted at position 77681930 of Chromosome 9 upstream of the critical exon 2 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 2 at position 77682710. The critical exon 2 is thus flanked by loxP sites. Flp-mediated recombination removed the lacZ/neo cassette and left exon 2 floxed.
  • mutations:
  • Insertion
  • synonyms:
  • Gclc<fl>,
  • Gclc<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories