| Primary Identifier | MGI:5476468 | Allele Type | Targeted |
| Gene | Gt(ROSA)26Sor | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| description | This allele was generate from Gt(ROSA)26Sortm1Mgn. |
| molecularNote | This allele was created by RMCE in Gt(ROSA)26Sortm1Mgn. The original selections cassettes (puromycin N-acetyltransferase and a truncated form of HSV1 thymidine kinase and EM7-driven neomycin resistance) were replaced by a cassette composed of ROSA26 upstream sequence deleted from the start codon to -228, 8 copies of the 50-bp activin response element (ARE) from the Xenopus laevis Mix1b promoter controlling expression of the mCherry reporter. An upstream FLP flanked hygromycin selection cassette was subsequently removed by flp recombinase. |
