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Allele : Tg(CDX2-cre/ERT2)752Erf transgene insertion 752, Eric Fearon

Primary Identifier  MGI:5477802 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(CDX2-cre/ERT2)752Erf
Strain of Origin  (C57BL/6J x SJL/J) Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a creERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain), and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic mice from founder line 752 were bred to C57BL/6J mice. The donating investigator reports that this strain was maintained by breeding hemizygous mice with C57BL/6J inbred mice for at least 4 generations.
  • mutations:
  • Insertion
  • synonyms:
  • CDX2P9.5-NLSCre,
  • CDX2-creERT2,
  • CDX2P9.5-NLSCre,
  • CDX2-creERT2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

1 Driven By

32 Publication categories