| Primary Identifier | MGI:5478737 | Allele Type | Chemically induced (ENU) |
| Gene | Fgf5 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | Capillary sequencing of the mutated gene identified a C to T transition at base pair 98261987 (v38) on chromosome 5 in the GenBank genomic region NC_000071 encoding Fgf5 (LOD = 4.56). The mutation corresponds to residue 394 in the mRNA sequence in exon 2 of 3 total exons. The mutation results in a substitution of arginine (R) to a premature stop codon at residue 132, and may cause nonsense-mediated decay of the transcript. |
