| Primary Identifier | MGI:5478538 | Allele Type | Targeted |
| Attribute String | Dominant negative | Gene | Kcnq5 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A mutation was introduced into exon 6 which changed the first glycine of the GYG signature pore sequence to serine (G278S) and a floxed neo resistance cassette was inserted in intron 5. Subsequent cre expression excised the resistance cassette in properly targeted ES cells. |