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Allele : Kcnq5<tm1.1Tjj> potassium voltage-gated channel, subfamily Q, member 5; targeted mutation 1.1, Thomas J Jentsch

Primary Identifier  MGI:5478538 Allele Type  Targeted
Attribute String  Dominant negative Gene  Kcnq5
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A mutation was introduced into exon 6 which changed the first glycine of the GYG signature pore sequence to serine (G278S) and a floxed neo resistance cassette was inserted in intron 5. Subsequent cre expression excised the resistance cassette in properly targeted ES cells.
  • mutations:
  • Single point mutation
  • synonyms:
  • Kcnq5<dn>,
  • Kcnq5<dn>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories