Primary Identifier | MGI:5486022 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase, Transactivator | Gene | Tg(Sftpc-rtTA,Nudt18-tetO-cre)1Ptch |
Strain of Origin | CD-1 | Induced With | doxycycline/tetracycline |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A BAC clone spanning the Sftpc (SPC) and Nudt18 genomic regions of mouse chromosome 14 was modified to insert a reverse tetracycline transactivator sequence at the start ATG of the Sftpc locus. A second round of recombination was performed to insert a cre recombinase sequence under the control of the tetracycline responsive element (tetO) at the start ATG of the Nudt18 gene. Founder information was not available. |