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Allele : Rbbp8<tm1.1Thl> retinoblastoma binding protein 8, endonuclease; targeted mutation 1.1, Thomas Ludwig

Primary Identifier	MGI:5484516	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Rbbp8
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 2, which encodes the N-terminal 36 amino acids and contains the translation initiation site, was floxed. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of exon 2.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
CtIP<co>,
CtIP<co>

earliestPublication:
Bothmer A, et al. (2013) Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. J Exp Med 210(1):115-23

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

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