| First Author | Aqrabawi AJ | Year | 2020 |
| Journal | Nat Commun | Volume | 11 |
| Issue | 1 | Pages | 1246 |
| PubMed ID | 32144256 | Mgi Jnum | J:287254 |
| Mgi Id | MGI:6401684 | Doi | 10.1038/s41467-020-15032-2 |
| Citation | Aqrabawi AJ, et al. (2020) Olfactory memory representations are stored in the anterior olfactory nucleus. Nat Commun 11(1):1246 |
| abstractText | The anterior olfactory nucleus (AON) is the initial recipient of odour information from the olfactory bulb, and the target of dense innervation conveying spatiotemporal cues from the hippocampus. We hypothesized that the AON detects the coincidence of these inputs, generating patterns of activity reflective of episodic odour engrams. Using activity-dependent tagging combined with neural manipulation techniques, we reveal that contextually-relevant odour engrams are stored within the AON and that their activity is necessary and sufficient for the behavioural expression of odour memory. Our findings offer a new model for studying the mechanisms underlying memory representations. |
