| Primary Identifier | MGI:5486166 | Allele Type | Targeted |
| Attribute String | Modified regulatory region, Null/knockout | Gene | Rr26 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 7.5kb genomic fragment containing the Gremlin cis regulatory region was digested from BAC RP23-113H17 and a loxP site was inserted upstream and an FRT site flanked neomycin resistance gene cassette and a second loxP cassette downstream of the enhancer (chr2:113640843-113641280, Build 38). After homologous recombination, cre-mediated recombination removed the enhancer/silencer and selection cassette. The enhancer regulates Grem1 but is located in intron 13 of Fmn1. |
