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Allele : Or8a1<tm38Mom> olfactory receptor family 8 subfamily A member 1; targeted mutation 38, Peter Mombaerts

Primary Identifier  MGI:5489815 Allele Type  Targeted
Attribute String  Hypomorph, Reporter Gene  Or8a1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Two amino acid substitutions, D121R and R122D, were made in this targeted mutation to interfere with G protein coupling via the highly conserved DRY motif, and an IRES-taulacZ reporter sequence was inserted downstream for bicistronic expression.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • M71-RDY,
  • M71-RDY,
  • M71(RDY)-lacZ,
  • M71(RDY)-lacZ
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele