| Primary Identifier | MGI:5491025 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Prnp*P101L)2866Sbp |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene construct consists of the mouse Prnp containing a substitution of a leucine for proline codon at residue 101, corresponding to the Gerstmann-Straussler-Scheinker disease mutation at codon 102 of the human PRNP gene, in the cosSHa.Tet vector. This line overexpresses the transgene about 8-fold. Three lines were generated; 2247, 2866, and 2862. |
