| Help | About | Contact Us

Allele : Tg(Prnp-CCS)17Jlel transgene insertion 17, Jeffrey L Elliott

Primary Identifier	MGI:5492387	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Prnp-CCS)17Jlel
Strain of Origin	B6SJLF1	Is Recombinase	false
Is Wild Type	false

molecularNote

Human wild type copper chaperone for SOD1 cDNA was cloned into a mouse prion protein promoter construct. Line 17 showed the highest levels of expression in the spinal cord.

mutations:
Insertion

earliestPublication:
Son M, et al. (2007) Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology. Proc Natl Acad Sci U S A 104(14):6072-7

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76470151

MouseMine