Primary Identifier | MGI:5491539 | Allele Type | Targeted |
Attribute String | Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct introduced a floxed STOP cassette followed by an mCherry and the ubiquitylation domains of human CDT1 (amino acids 30 to 120) fusion. Cre-mediated recombination removed the STOP cassette. This fluorescent ubiquitylation-based cell cycle indicator accumulates in the nuclei during G1 phase of the cell cycle. |