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Allele : L1cam<tm4.1Vlem> L1 cell adhesion molecule; targeted mutation 4.1, Vance Lemmon

Primary Identifier  MGI:5491826 Allele Type  Targeted
Gene  L1cam Transmission  Germline
Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og Is Recombinase  false
Is Wild Type  false
molecularNote  This allele encodes a protein truncated at amino acid position 1152. The mutation of codon 1176 to a STOP codon results in disrupted splicing and skipping of exon 27. Cre-mediated recombination removed the floxed neo cassette inserted into intron 26. Western blot analysis confirmed expression of the truncated protein in the brain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • L1<1152>,
  • L1<1152>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories