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Allele : Smg6<Tg(SMN1*delta5)1Pks> SMG6 nonsense mediated mRNA decay factor; transgene insertion 1, Nick Parkinson

Primary Identifier  MGI:5493450 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Smg6
Strain of Origin  (C57BL/6 x CBA)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Mice with this transgenic insertion express a cDNA splice isoform of human SMN1 that lacks exon 5 under control of the ~750-bp SMN1 minimal promoter. The transgene is stably integrated as a single copy into intron 13 of the Smg6 locus. Expression of the transgene has been detected in all tissues analyzed.
  • mutations:
  • Insertion
  • synonyms:
  • SMNDelta5,
  • Tg(SMN1*delta5-Smg6)1Pks,
  • Tg(SMN1*delta5-Smg6)1Pks,
  • SMNDelta5
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories