Primary Identifier | MGI:5493450 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Smg6 |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Mice with this transgenic insertion express a cDNA splice isoform of human SMN1 that lacks exon 5 under control of the ~750-bp SMN1 minimal promoter. The transgene is stably integrated as a single copy into intron 13 of the Smg6 locus. Expression of the transgene has been detected in all tissues analyzed. |