| Primary Identifier | MGI:5495816 | Allele Type | Targeted |
| Gene | Ddc | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Intron 6 was replaced with a modified intron 6 with a mutation (A to T) 4 nucleotides into the intron affecting the exon 6 splice acceptor site, and a floxed neomycin resistance cassette. Cre-mediated recombination removed the neomycin resistance cassette. Western blot analysis confirmed the lack of expression in the substantia nigra. |
