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Allele : Gt(ROSA)26Sor<tm4(EWSR1/ATF1)Mrc> gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Mario R Capecchi
Primary Identifier  MGI:5495288 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA clone was produced using RNA purified from a confirmed "clear cell sarcoma" tumor. The cDNA contained the EWSR1/ATF1 fusion product of the t(12;22) chromosomal translocation typical of these tumors. This cDNA was inserted downstream of a floxed pgk-neomycin cassette and upstream of an IRES-EGFP. Stop codons in the neomycin cassette prevent EWSR1/ATF1 and EGFP expression.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm2(EWSR1/ATF1)Mrc>,
  • Gt(ROSA)26Sor<tm2(EWSR1/ATF1)Mrc>
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories





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