| Primary Identifier | MGI:5496904 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Aloxe3 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxp site was inserted downstream of exon 5. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 5 floxed. Cre-mediated recombination removed exons 2 through 5. Western blot analysis confirmed the absence of protein expression in neonatal mouse epidermis. |