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Allele : Rraga<tm1.1Dmsa> Ras-related GTP binding A; targeted mutation 1.1, David Sabatini
Primary Identifier  MGI:5499905 Allele Type  Targeted
Attribute String  Constitutively active Gene  Rraga
Transmission  Germline Strain of Origin  129 and C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed hygromycin resistance/STOP cassette was inserted upstream of a modified coding exon in which an A to T transversion results in the amino acid substitution of lysine for glutamine at position 66 (Q66L). Cre-mediated recombination removed the hygromycin resistance/STOP cassette. The predicted protein is constitutively active.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • RagA<GTP>,
  • RagA<Q66L>,
  • RagA<GTP>,
  • RagA<Q66L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

9 Publication categories

Trail: Allele




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